Many trials, particularly those for treatments of psychiatric disorders or pain, involve the use of human raters. This article looks at how human raters can contribute to apparently high placebo […]
After careful review of internal and external data, as well as published explanations for high “placebo response rates” in clinical depression trials (much of which also applies to clinical trials in general), three factors emerged as being of particular importance because they are easily mitigated by proper trial design, thorough research staff training, and meticulous oversight of study conduct.
