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Our History

Clinical Research with Agility and Adaptability

Rho is a full-service contract research organization optimally sized to deliver results from clinical research with agility and adaptability. Maximizing profitability, stability, and planned growth has helped provide us with the experience, capacities, and capabilities of a larger organization—all without losing touch with our entrepreneurial passion.

From our headquarters in Chapel Hill, North Carolina, we employ more than 400 creative and critical thinkers. We provide excellent service to some of the nation’s leading pharmaceutical, biotechnology, and medical device companies as well as a number of federal agencies. Our experienced teams help our clients bring new products to the marketplace in a wide range of therapeutic areas.

A company history built on a commitment to excellence

Rho began in 1984 as the vision of two people—a nationally recognized biostatistician and the head of clinical data management for one of the most respected child development research institutes in the country. From the basement of their home, the husband and wife team of Ron and Mary Helms created a highly specialized organization designed to enhance the quality and speed of pharmaceutical and biotech clinical research. Academic careers involving cutting-edge clinical research in a variety of therapeutic areas instilled the Helmses with a deep understanding of the importance of quality in all aspects of clinical research. From that deep understanding grew a passion. It’s a passion for quality and excellence that continues to drive Rho more than 30 years later.

Rooted in principle

From the start, the Helmses have encouraged a culture where critical and creative thinking establishes a reputation for quality, integrity, and productivity. From humble beginnings to present day, our extensive portfolio of clinical research solutions has expanded, and our reputation for great people doing great work has never been stronger.

"Our commitment is to deliver the highest quality work product and meet aggressive deadlines without sacrificing integrity or rigor."

–Ronald W. Helms, Ph.D., & Mary W. Helms