Respiratory
Cystic Fibrosis
Committed to Global Cystic Fibrosis Research
With any cystic fibrosis program, building and maintaining strong relationships is critical. For this reason, we make a concerted effort to keep our cross-functional cystic fibrosis study teams together over the course of multiple studies—aiding development of our therapeutic indication expertise and strengthening our relationships with key opinion leaders and clinical sites in North America and Europe.
Why Choose Rho?
Rho understands what it takes to successfully execute global cystic fibrosis (CF) studies. Not only have we conducted studies of both pulmonary and gastrointestinal outcomes through inpatient and outpatient studies, we also have extensive relationships with the key CF clinical trials networks – the Cystic Fibrosis Foundation Therapeutics Development Network (CFF TDN), the European Cystic Fibrosis Society (ECFS) Clinical Trials Network, and Cystic Fibrosis Canada Accelerating Clinical Trials (CF CanACT) – including a comprehensive understanding of their protocol assessment and feasibility processes.
Expertise in Action
Our team of CF experts average 10+ years dedicated to CF clinical research and have experience coordinating standard of care with study-specific procedures and assessments, interacting with multidisciplinary care teams, Non-CFTR modulator studies, and working with the CFF TDN data safety monitoring board (DSMB). Our dedication and passion to find a cure extends to working with patient advocacy groups as well, including a strong partnership with Emily’s Entourage where the focus is to find cures for the last 10% of CF patients. With our proven success in CF trial management, strong site relationships, and global reach, Rho is the right CRO partner to help you navigate the complexities involved with CF studies.
Some highlights include:
-
Long-standing relationships with 75+ CF research centers globally, including those in the Cystic Fibrosis Foundation Therapeutics Development Network (CFF TDN), European Cystic Fibrosis Society Clinical Trials Network (ECFS CTN), and Cystic Fibrosis Canada Accelerating Clinical Trials (CF CanACT) network
- Strong partnership with advocacy groups including Emily’s Entourage, whose focus is to find cures for the last 10%
- Rho is the only CRO to form a partnership with the CFF TDN
- Rho conducts quarterly meetings with CFF TDN
Rho has experience with
- CF Gene Therapy
- Phage
- PERT/GI
- Oral and Inhalation Studies
- In-patient
- Anti-infectives
Expertise with Common CF Assessments & Endpoints
- CFA/CNA
- CFQ-R/CRISS
- FEV1/FVC
- Gene therapy
- MCC/LCI
- Spirometry
- Sputum Collection
Relationships with
75+
CF research centers globally (CFF TDN, ECFS CTN, and CanACT networks)
In the past 3 years, we have conducted
11 studies and 1 marketing application
Case Study: Rho and Anthera Pharmaceuticals’ Collaborative Partnership in Cystic Fibrosis
In this case study, Rho and Anthera Pharmaceuticals collaborated in developing a product to treat Cystic Fibrosis. Read more about this partnership.
Some of the Sites We’ve Worked With Include
- University of Alabama; Birmingham, AL
- Johns Hopkins University; Baltimore, MD
- Virginia Commonwealth University; Richmond, VA
- Northwestern University; Chicago, IL
- University of California San Diego; San Diego, CA
- University Hospitals Cleveland Medical Center; Cleveland, OH
- Children’s Hospital Colorado; Aurora, CO
- University of Kansas Medical Center; Kansas City, KS
- Nationwide Children’s Hospital; Columbus, OH
- National Jewish Health; Denver, CO
- University of Florida; Gainesville, FL
- University of North Carolina at Chapel Hill; Chapel Hill, NC
- Hershey Medical Center Pennsylvania State University; Hershey, PA
- Boston Children’s Hospital; Boston, MA
- University of Pennsylvania; Philadelphia, PA
- Children’s Hospital of Pittsburgh of UPMC; Pittsburgh, PA
- Żagiel-Med Szpital; Lublin, Poland
- Medical University of South Carolina; Charleston, SC
- Cassia Villa Medica ul Słoneczna; Rabka-Zdrój, Poland
- Tüdőgyógyintézet Törökbálint; Törökbálint, Hungary
- Podkarpacki Osrodek Pulmonologii i Alergologii; Rzeszów, Poland
- Sanatorium “ Kamienny Potok”; Sopot, Poland
- Hospital La Fe de Valencia; Valencia, Spain
- Pediatric Pulmonary Medicine: Department at the Ruth Rapport Children’s Hospital; Haifa, Israel
- Stollery Children’s Hospital/University of Alberta; Edmonton, AB
- Hadassah University Hospital Ein Kerem; Jerusalem, Israel
- Magyar Imre Kórház; Ajka, Hungary
- Unity Health Toronto – St. Michael’s Hospital; Toronto, ON
- McGill University Health Center; Montreal, QU
CF Experience
Phase | Sites | Patients |
I | 5 | 16 |
I | 39 | 60 |
IB | 20 | 32 |
I/II | 6 | 32 |
I/II | 15 | 21 |
II | 8 | 24 |
II | 14 | 40 |
II | 28 | 114 |
III | 20 | 54 |
III | 40 | 138 |
III | 57 | 60 |
III | 60 | 380 |
Join us in our commitment to respiratory research as we passionately fight to help those affected by respiratory diseases breathe a little easier. We proudly invite you to experience Rho.
Webinar
Building Bridges: Patient Advocacy Groups Can Be Vital Partners in Clinical Research Trials
Patient advocacy is vital for advancement in managing disease. We met with Chandrabali Ghose-Paul, Chief Scientific Officer, Emily’s Entourage and Gary Joyner, Chairman Emeritus, Board of Directors, Primary Ciliary Dyskinesia (PCD) Foundation to discuss the role of patient advocacy groups in clinical research. In this webinar, we discuss building the gap between research and patients and how to support patient advocacy in our community.
Watch WebinarCaitlin Hirschman, R.N.
Principal Clinical Team Lead
Shannon Kirby
Clinical Team Lead
Success Stories
Rho not only gave Anthera a clear picture of how their team would fulfill the study needs but showed their knowledge and expertise of cystic fibrosis as well as the protocol in a way that made them a collaborative partner rather than a service provider.
Former VP of Clinical Operations at Anthera
Join us in our commitment to Cystic Fibrosis research as we passionately fight to help those affected by CF live a full and independent life. We proudly invite you to experience Rho.